{"id":11,"date":"2019-10-08T17:47:53","date_gmt":"2019-10-08T17:47:53","guid":{"rendered":"http:\/\/saterialelab.com\/?page_id=11"},"modified":"2025-08-11T15:32:45","modified_gmt":"2025-08-11T15:32:45","slug":"research","status":"publish","type":"page","link":"http:\/\/saterialelab.com\/","title":{"rendered":"Research"},"content":{"rendered":"\n<p style=\"font-size:18px\">Our lab studies a parasite named <em>Cryptosporidium<\/em> that invades, grows, and replicates within cells that line the intestine. This parasite can live in a very wide range of vertebrate hosts&#8230; there are species that infect mammals, birds, amphibians, reptiles&#8230; even fish. In humans, <em>Cryptosporidium<\/em> is a common infection that causes a severe, but typically self-limiting, diarrheal disease. In malnourished or immunocompromised patients, however, these infections can be life threatening. Young children are also highly susceptible to <em>Cryptosporidium<\/em> and disproportionately bear the brunt of disease. <\/p>\n\n\n\n<p style=\"font-size:18px\">Despite this serious impact on public health, there are no effective treatments and the knowledge base to drive their development is lacking. Put simply, very little is known about how the parasite establishes infection and how the immune system detects and responds. Using a combination of genetic and molecular tools, we study <em>Cryptosporidium<\/em> infection and immunity to expand this knowledge base. Our hope is that a better understanding of the host-parasite interactions will open up new avenues for therapy and prevention of disease.<\/p>\n\n\n\n<p style=\"font-size:18px\"><strong><em>Research highlighted in:<\/em><\/strong><\/p>\n\n\n\n<p style=\"font-size:18px\"><em><a href=\"https:\/\/doi.org\/10.1016\/j.chom.2019.06.008\">Cell Host &amp; Microbe &#8211; &#8216;Exciting Contributions to the Cryptosporidium Renaissance<\/a><\/em><a href=\"https:\/\/doi.org\/10.1016\/j.chom.2019.06.008\">&#8216;<\/a><\/p>\n\n\n\n<p style=\"font-size:18px\"><a href=\"https:\/\/doi.org\/10.1038\/nature14636\">Nature &#8211; &#8216;<em>CRISPR for Cryptosporidium<\/em>&#8216;<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our lab studies a parasite named Cryptosporidium that invades, grows, and replicates within cells that line the intestine. This parasite can live in a very wide range of vertebrate hosts&#8230; there are species that infect mammals, birds, amphibians, reptiles&#8230; even fish. In humans, Cryptosporidium is a common infection that causes a severe, but typically self-limiting, &hellip; <\/p>\n<p class=\"link-more\"><a href=\"http:\/\/saterialelab.com\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Research&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":273,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-11","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":41,"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":481,"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/pages\/11\/revisions\/481"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/media\/273"}],"wp:attachment":[{"href":"http:\/\/saterialelab.com\/index.php\/wp-json\/wp\/v2\/media?parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}